Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

The San Francisco 49ers entered Sunday night's matchup against the Buffalo Bills at Highmark Stadium without several key ...

San Francisco 49ers cornerback Renardo Green breaks up Buffalo Bills quarterback Josh Allen's improvised loft to Bills wide ...

The Bills return from their bye and will look to keep pace with the Kansas City Chiefs at the top of the AFC. Josh Allen has ...

San Francisco 49ers running back Christian McCaffrey bulldozes a Buffalo Bills defender into to the snowy gridiron during a 20-yard run.

San Francisco 49ers running back Christian McCaffrey suffered another injury in just his fourth game of the season. During ...

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers running back Christian McCaffrey (23) tries to avoid Buffalo ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

McCaffrey slid down untouched in the backfield after taking a toss, then immediately went to the 49ers’ medical tent and ...

Christian McCaffrey was off to a great start in Sunday night’s matchup with the Bills but had to exit the contest early in ...

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...