San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

The 49ers got blown out by the Packers in Week 12 and rookie wideout Ricky Pearsall was held without a catch for the second ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.

It seems like Trent Williams will miss his second game in a row this weekend with an ankle injury. Williams didn't practice ...

According to Matt Barrows of The Athletic, San Francisco 49ers quarterback Brock Purdy (shoulder) remained a limited ...

Picking a D/ST in fantasy can make or break your week. Here are the ones you should target and the ones to avoid in Week 13.