The four-time defending AFC Champs squared off against the Detroit Lions in one of a number of Thanksgiving matchups between ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

The NFL star Buffalo Bills quarterback is a 6-foot-5 mountain of a man. For two kids given a dream come true, one of them ...

With the Bills (9-2) on the cusp of a fifth straight AFC East division title, the pressure is on Allen and Co. to deliver the ...

Buffalo Bills quarterback Josh Allen and coach Sean McDermott reacted to forecasts of a snow game against the San Francisco ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

The Buffalo Bills look set to face the San Francisco 49ers in wild conditions with heavy snow continuing to fall in the area ...

Now that the holiday season is in full swing, several Bills players are taking the time to be active in the community. A ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay.