It seems like Trent Williams will miss his second game in a row this weekend with an ankle injury. Williams didn't practice ...

San Francisco 49ers left tackle Trent Williams may be at risk of missing his second consecutive game. On Sunday, the ...

San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.

San Francisco 49ers offensive tackle Trent Williams was seen in the locker room on Wednesday using a scooter as he recovers ...

Brock Purdy was listed as limited for Wednesday's practice by San Francisco 49ers head coach Kyle Shanahan, suggesting some ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

The San Francisco 49ers received important Brock Purdy, Trent Williams and Nick Bosa injury updates on Wednesday.

Williams missed the 49ers' Week 12 loss to the Packers. Jaylon Moore got the start at left tackle in his place and would likely handle those duties again Sunday in Buffalo if Williams is unable to ...

On his “Cleats and Convos with Deebo Samuel” podcast, Deebo Samuel was asked about the idea that Kyle Shanahan could be out at the end of the year.

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

Bills: The Buffalo Bills were off in Week 12, so they didn’t move in our rankings. They are still the clear No. 2 team in the ...

The 49ers are taking stock of their injury situation but could be getting some key players back for Buffalo game.