San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

Saquon Barkley ran for 107 yards and a touchdown and the Philadelphia Eagles defeated the host Baltimore Ravens 24-19 on Sunday for their eighth consecutive victory.

Christian McCaffrey was having a resurgent game against the Buffalo Bills. He finally looked like the player who was supposed ...

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

San Francisco 49ers running back Christian McCaffrey was running wild against the Buffalo Bills on Sunday Night Football.

The 49ers season is still trending down and now they're searching for answers on if they can get back on track.

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers running back Christian McCaffrey (23) tries to avoid Buffalo ...

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

San Francisco coach Kyle Shanahan told reporters postgame that their star running back had injured the posterior cruciate ...