The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

The Detroit Lions won't face Christian McCaffrey in Week 17 this season. The San Francisco 49ers running back injured the PCL ...

The 49ers are down to one healthy RB, rookie Isaac Guerendo. They will likely elevate Patrick Taylor Jr. from the practice ...

It's going to be another lost season for Christian McCaffrey, but he is not the only San Francisco running back who suffered ...

The San Francisco 49ers' dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the ...

The San Francisco 49ers entered Sunday night's matchup against the Buffalo Bills at Highmark Stadium without several key ...

The disastrous season for the San Francisco 49ers continued Monday with word of both the team's top running backs out for ...

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup ...

San Francisco 49ers running back Christian McCaffrey and top backup Jordan Mason are being placed on injured reserve. Read ...